Compile Data Set for Download or QSAR
maximum 50k data
Found 490 of ic50 data for polymerid = 5266,5546,7343
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478381(CHEMBL256111)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478380(CHEMBL257190)
Affinity DataIC50:  0.330nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50479470(CHEMBL489586 | MK-4965)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of HIV1 isolate R8 reverse transcriptase K103N mutant after 90 mins by electrochemiluminescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50479471(CHEMBL491019 | MK-1107)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of HIV1 RT polymerase K103N mutant by SPAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50479470(CHEMBL489586 | MK-4965)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of HIV1 RT polymerase K103N mutant by SPAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478040(CHEMBL198347)
Affinity DataIC50:  0.891nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478026(CHEMBL203420 | GW678248 | GW8248)
Affinity DataIC50:  1nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478025(CHEMBL199409)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478383(CHEMBL402823)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of HIV1 RT polymerase K103N mutant by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478383(CHEMBL402823)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478385(CHEMBL257172)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50103642(4-(6-amino-5-bromo-2-(4-cyanophenylamino)pyrimidin...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of HIV1 isolate R8 reverse transcriptase K103N mutant after 90 mins by electrochemiluminescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50479472(CHEMBL523972)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of HIV1 RT polymerase K103N mutant by SPAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478378(CHEMBL403409)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478050(CHEMBL199328)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478048(CHEMBL199539)
Affinity DataIC50:  2nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478032(CHEMBL275658 | GW4511 | GW564511 | GW69564)
Affinity DataIC50:  2nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478047(CHEMBL201793)
Affinity DataIC50:  3nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478026(CHEMBL203420 | GW678248 | GW8248)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478044(CHEMBL201485)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478387(CHEMBL255689)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478027(CHEMBL201343)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50479473(CHEMBL491018)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of HIV1 RT polymerase K103N mutant by SPAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50485779(CHEMBL2163850)
Affinity DataIC50: >4nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I mutant RNA-dependent DNA polymerase activity using poly(rA)/oligo(dT)10:1 and [3H]-dTTP substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478046(CHEMBL202663 | GW3011)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478022(CHEMBL202929)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478053(CHEMBL427371)
Affinity DataIC50:  5nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478028(CHEMBL198398)
Affinity DataIC50:  5nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478379(CHEMBL401809)
Affinity DataIC50:  6nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478030(CHEMBL426480)
Affinity DataIC50:  6nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50482849(CHEMBL1258364)
Affinity DataIC50:  6nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478036(CHEMBL199506)
Affinity DataIC50:  6nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50482847(CHEMBL1258135)
Affinity DataIC50:  6nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478049(CHEMBL203313)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478029(CHEMBL201527)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478388(CHEMBL255468)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50476899(CHEMBL232963)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C mutant by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50482845(CHEMBL1257905)
Affinity DataIC50:  8nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50485778(CHEMBL2163488)
Affinity DataIC50:  8nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I mutant RNA-dependent DNA polymerase activity using poly(rA)/oligo(dT)10:1 and [3H]-dTTP substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50476896(CHEMBL232576)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C mutant by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478034(CHEMBL201526)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50230553(3-Benzenesulfonyl-5-chloro-2-(5-methyl-1H-imidazol...)
Affinity DataIC50:  9nMAssay Description:Inhibition of HIV NL43 recombinant reverse transcriptase K103N mutant by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50476847(CHEMBL234401)
Affinity DataIC50:  9nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I mutant by RNA-dependent DNA polymerase activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183201(CHEMBL379722 | N-(2-chloro-4-sulfamoyl-phenyl)-2-[...)
Affinity DataIC50:  10nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50481382(CHEMBL603276)
Affinity DataIC50:  10nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I mutant by RNA-dependent DNA polymerase activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50485779(CHEMBL2163850)
Affinity DataIC50: >10nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant RNA-dependent DNA polymerase activity using poly(rA)/oligo(dT)10:1 and [3H]-dTTP substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataIC50:  10nMAssay Description:Inhibition of HIV1 isolate R8 reverse transcriptase K103N mutant after 90 mins by electrochemiluminescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50483698(CHEMBL1766215)
Affinity DataIC50:  10nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I mutant expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478032(CHEMBL275658 | GW4511 | GW564511 | GW69564)
Affinity DataIC50: <10nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50497092(CHEMBL3263471)
Affinity DataIC50:  10nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase L1001 mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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